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Metabolic Fuel Mobilization

Meaning

Metabolic Fuel Mobilization is the acute physiological process of breaking down and releasing stored energy substrates, primarily glucose from glycogen and fatty acids from triglycerides, into the bloodstream for immediate use by active tissues. This process is rapidly initiated by the neuroendocrine response to stress or energy demand, such as intense exercise or fasting. Hormones like epinephrine, norepinephrine, and glucagon are the key regulatory signals that ensure adequate substrate availability to support high-performance activities. It is essential for maintaining energy homeostasis during periods of high metabolic need.