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Metabolic Flexibility Brain Fuel

Meaning

The brain’s inherent and vital capacity to readily and efficiently switch between different primary energy substrates, mainly glucose and ketone bodies, to consistently meet its exceptionally high metabolic demands. High metabolic flexibility in the brain is considered a robust marker of neurological resilience, ensuring a stable, uninterrupted energy supply even during periods of nutrient scarcity or significant peripheral insulin resistance. This essential adaptability is critical for sustained, high-level cognitive performance and comprehensive neuroprotection.