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Metabolic Dysfunction Biomarkers

Meaning

Metabolic Dysfunction Biomarkers are a panel of measurable physiological and biochemical indicators that signal a compromised state of energy utilization, nutrient processing, and homeostatic regulation, preceding the clinical diagnosis of metabolic syndrome or type 2 diabetes. These markers include elevated fasting glucose, high insulin resistance indices (like HOMA-IR), dyslipidemia, and altered adipokine profiles. Identifying these biomarkers allows for early intervention to restore insulin sensitivity and mitigate the cascade of hormonal imbalances that contribute to chronic disease. They are crucial for assessing true metabolic health.