What is the Origin of Metabolic Demand?

Rooted in bioenergetics and exercise physiology, the term describes the required output of energy conversion processes within the cell. It is a measure of required work load on the system.

What is the Mechanism of Metabolic Demand?

Increased metabolic demand, often driven by intense physical activity or cellular repair processes, triggers a cascade involving catecholamine release and increased glucagon and cortisol secretion to mobilize stored substrates like glycogen and triglycerides. The endocrine system adjusts insulin secretion dynamically to manage the resulting shifts in glucose homeostasis necessary to meet this acute or chronic requirement.

Metabolic Demand

Meaning

Metabolic Demand quantifies the total energy expenditure required by the body to sustain basal functions, perform physical activity, and manage thermoregulation under specific physiological conditions. This demand dictates substrate flux and subsequent hormonal signaling for energy mobilization. It is the body’s required energetic throughput.