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Metabolic Decoupling Prevention

Meaning

Metabolic Decoupling Prevention is a clinical strategy aimed at maintaining the tight, efficient coupling between the body’s energy consumption (metabolic rate) and its energy production (ATP synthesis), particularly within the mitochondria. Decoupling, which is an inefficiency where energy is released as heat instead of ATP, can lead to chronic fatigue and inefficient fuel utilization. The prevention strategy focuses on protecting mitochondrial integrity and ensuring the optimal function of the electron transport chain.