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Metabolic Crosstalk

Meaning

Metabolic crosstalk refers to the complex communication and reciprocal influence between distinct metabolic pathways, cellular compartments, or distant organs within a biological system. This systemic communication ensures coordinated regulation of energy homeostasis, nutrient utilization, and overall physiological balance. Cells and tissues do not operate in isolation; their metabolic activities are continually modulated by signals originating from other parts of the body.