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Metabolic Co-Regulation

Meaning

Metabolic Co-Regulation refers to the interdependent and simultaneous regulatory control exerted across multiple, distinct metabolic pathways within the body, ensuring energy balance and substrate availability are harmonized to meet the organism’s dynamic demands. This complex interplay involves the coordinated action of key endocrine hormones, including insulin, glucagon, cortisol, and thyroid hormones, which collectively influence glucose, lipid, and protein metabolism. Optimal metabolic co-regulation is fundamental to maintaining vitality, preventing chronic conditions like insulin resistance, and ensuring long-term health. Dysfunction in one pathway inevitably cascades to affect the functional efficiency of the others.