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Metabolic Clock Gene Expression

Meaning

Metabolic Clock Gene Expression refers to the rhythmic, oscillating activity of specific genes, known as core clock genes, that drive the timing of metabolic functions within peripheral tissues such as the liver, muscle, and adipose tissue. These synchronized oscillations ensure that energy processing pathways are optimally timed relative to feeding and fasting cycles. Dysregulation of this expression pattern leads to metabolic inflexibility, where tissues cannot efficiently switch between nutrient utilization modes. Maintaining the robust rhythm of these gene transcripts is a hallmark of sound metabolic endocrinology.