Metabolic Adaptation Threshold is the specific physiological point at which the body’s homeostatic mechanisms, in response to a sustained energy deficit or surplus, initiate powerful counter-regulatory hormonal and enzymatic changes to resist further alteration in body weight or composition. Crossing this threshold typically results in a plateau, where further progress requires a significant, strategic adjustment to the energy or activity stimulus. This concept underscores the biological resilience and defense of the body’s established energy setpoint.
Origin
This is a conceptual term derived from exercise physiology and clinical weight management, integrating metabolic adaptation (changes in energy expenditure) with the technical term threshold (a point that must be exceeded to produce a given effect). It is a key concept in explaining the common challenges of sustained weight management.
Mechanism
When energy intake is consistently restricted, the body crosses the threshold by reducing non-exercise activity thermogenesis (NEAT) and lowering the basal metabolic rate, often mediated by a reduction in active thyroid hormone (T3). Concurrently, the hormonal environment shifts dramatically: hunger hormones like ghrelin increase, while satiety signals like leptin decrease, creating a powerful physiological and psychological drive to return to the initial body composition setpoint.
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