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Metabolic Adaptation Science

Meaning

Metabolic Adaptation Science is the clinical and physiological study of the homeostatic changes in energy expenditure that occur in response to prolonged changes in caloric intake, most notably during periods of energy deficit. This adaptive process, often termed “adaptive thermogenesis,” involves a non-linear reduction in resting metabolic rate that is greater than predicted by the loss of body mass alone. Understanding this science is essential for managing weight loss plateaus and preventing weight regain, as the body attempts to defend its previous energy set point by becoming more fuel-efficient. Effective weight management strategies must proactively counteract these powerful, evolutionarily conserved adaptations.