The robust neurobiological and endocrine capacity to adapt effectively in the face of stress, adversity, and psychological challenge, maintaining or quickly returning to a stable functional state. This foundation is clinically supported by a well-regulated Hypothalamic-Pituitary-Adrenal (HPA) axis and balanced neurotransmitter profiles. A strong foundation is essential for protecting against chronic stress-induced hormonal dysfunction and promoting emotional stability.
Origin
This is a concept blending psychology, neuroscience, and endocrinology, where “resilience” is understood as an active, biologically underpinned process of adaptation. The “foundation” emphasizes the prerequisite physiological stability required for sustained mental well-being and cognitive function. It moves beyond simple coping to focus on the underlying biological capacity for robust adaptation.
Mechanism
The foundation relies on the HPA axis’s ability to mount an appropriate, transient cortisol response to a stressor and, critically, to rapidly shut down the response via efficient negative feedback loops. Furthermore, balanced levels of key neurotransmitters like serotonin and dopamine, regulated by neurotrophic factors, contribute to emotional stability and cognitive flexibility. Chronic, unmanaged stress degrades this mechanism by dampening receptor sensitivity and impairing feedback.
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