Mental Energy Sustainment is the physiological capacity to maintain consistent, high-level cognitive function, including focus, executive function, and working memory, without experiencing significant mid-day dips or fatigue. This state is distinct from transient stimulation, relying instead on stable glucose metabolism, robust neurotransmitter balance, and efficient cerebral blood flow. Clinical strategies focus on optimizing the underlying neurobiological and hormonal systems that govern brain fuel and signaling.
Origin
This term is a functional, patient-centric concept rooted in neuroendocrinology and metabolic psychiatry, moving beyond subjective descriptions of fatigue. “Sustainment” implies a continuous, regulated energy supply, reflecting the clinical goal of enduring cognitive vitality throughout the waking day.
Mechanism
Sustainment is critically dependent on a stable supply of ATP to neurons and glia, often achieved by maintaining euglycemia and mitochondrial efficiency. Hormones play a significant role, with optimal thyroid hormone levels supporting cerebral metabolism and balanced cortisol promoting alertness without inducing excitability. Furthermore, the regulated turnover and availability of key neurotransmitters, such as dopamine and acetylcholine, are essential for maintaining focus and cognitive drive.
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