Menopause Health encompasses the comprehensive physiological, psychological, and clinical management of women transitioning through and living beyond the permanent cessation of ovarian function and menstrual cycles. This area of focus addresses the systemic effects of estrogen and progesterone withdrawal, which extend beyond reproductive changes to include cardiovascular, skeletal, cognitive, and metabolic health. Optimal Menopause Health is a proactive clinical strategy aimed at mitigating the increased risk of chronic diseases associated with this life stage and preserving quality of life. It requires a holistic, individualized approach to care.
Origin
The term “Menopause” is derived from the Greek men (month) and pausis (a cessation), describing the natural biological event. “Menopause Health” is a modern clinical construct that shifts the focus from merely managing symptoms to proactively optimizing long-term well-being during and after this endocrine transition. It is a central domain within gynecology and preventive endocrinology.
Mechanism
The fundamental mechanism involves the dramatic decline in ovarian steroidogenesis, particularly the loss of estrogen and progesterone feedback on the hypothalamic-pituitary-gonadal (HPG) axis. This hormonal withdrawal impacts estrogen-sensitive tissues throughout the body, leading to vasomotor symptoms due to hypothalamic thermoregulation disruption and accelerated bone resorption due to loss of osteoprotective signaling. Furthermore, the altered hormonal milieu can contribute to changes in lipid metabolism and neurocognitive function.
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