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Menopause and Brain Changes

Meaning

Menopause and Brain Changes refers to the cascade of neurobiological, metabolic, and structural alterations that occur in the female brain due to the significant and permanent decline in ovarian estrogen production. These changes can manifest clinically as transient symptoms, including “brain fog,” impaired verbal memory, and changes in mood and thermoregulation. The brain, being a major target organ for estrogen, undergoes a metabolic shift that requires careful clinical management to support long-term cognitive health and mitigate the risk of neurodegenerative conditions. This transition represents a profound neuroendocrine event.