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Melatonin Synthesis Kinetics

Meaning

Melatonin Synthesis Kinetics refers to the quantitative study of the rate and pattern of production of the hormone melatonin within the pineal gland, particularly in response to the light-dark cycle. This includes the timing of its nocturnal rise, the magnitude of its peak concentration, and the rate of its clearance from circulation. Optimal kinetics are characterized by a sharp, robust nocturnal peak, which is essential for signaling biological night to the entire system and supporting restorative sleep. Disruptions to these kinetics are a clinical hallmark of circadian misalignment.