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Melatonin Suppression Dynamics

Meaning

The quantifiable and time-sensitive process by which exposure to light, particularly blue-spectrum light, inhibits the nocturnal synthesis and secretion of the hormone melatonin from the pineal gland. The “dynamics” refer to the dose-response relationship, where the intensity, spectrum, duration, and timing of light exposure directly determine the degree of suppression. Clinically, managing these dynamics is crucial for preserving the integrity of the circadian rhythm and optimizing sleep quality, as melatonin is the primary hormonal signal for darkness and sleep onset.