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Melatonin Supplementation

Meaning

Melatonin supplementation involves the exogenous administration of the hormone melatonin, which is naturally produced by the pineal gland, primarily in response to darkness. Clinically, it is most commonly utilized to help regulate the circadian rhythm, treat sleep disorders like insomnia, and alleviate symptoms of jet lag. Melatonin acts as a potent chronobiotic, influencing the timing of sleep, but it also possesses significant antioxidant and immunomodulatory properties. Appropriate use requires careful consideration of timing and dosage relative to an individual’s specific sleep-wake cycle.