A set of clinical and behavioral guidelines designed to maximize the body’s endogenous production and effective signaling of melatonin for improved sleep quality, enhanced antioxidant status, and circadian rhythm alignment. These protocols focus on environmental, nutritional, and timing strategies rather than relying solely on exogenous supplementation. The goal is to restore the natural, robust nocturnal melatonin surge.
Origin
These protocols are derived from chronotherapy and sleep hygiene principles, emphasizing the natural, light-dark-regulated production of the hormone. Optimization involves removing inhibitory factors and providing necessary precursors and environmental cues. The clinical focus is on supporting the pineal gland’s inherent capacity.
Mechanism
The core mechanism involves rigorous light hygiene, specifically minimizing blue light exposure in the evening, which is a potent inhibitor of melatonin synthesis. Protocols also incorporate precursor support, such as adequate tryptophan and vitamin B6 intake, and consistent timing of sleep and wakefulness to reinforce the natural circadian signal, thereby ensuring a robust and timely nocturnal melatonin surge.
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