Skip to main content

Melatonin Integrity

Meaning

Melatonin Integrity refers to the robust, appropriate, and rhythmic secretion pattern of the neurohormone melatonin from the pineal gland, reflecting the fidelity of the body’s internal circadian clock. Optimal integrity is characterized by a rapid, substantial increase in serum melatonin shortly after the onset of darkness, followed by a sustained nocturnal peak and a rapid morning decline. This hormonal rhythm is crucial for signaling darkness to the entire body, thereby regulating sleep onset, antioxidant defense, and the synchronization of peripheral hormonal rhythms.