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Melatonin Cascade Timing

Meaning

Melatonin Cascade Timing refers to the precise, chronobiologically correct initiation and peak of the nocturnal synthesis and secretion of the hormone melatonin by the pineal gland, a process that is fundamentally dictated by the absence of light exposure. Accurate timing of this cascade is paramount for regulating the sleep-wake cycle, synchronizing other hormonal rhythms, and maximizing the hormone’s powerful antioxidant and immune-modulating effects. Disruptions in this timing signal systemic circadian misalignment.