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Melanocortin Receptor Agonists

Meaning

Melanocortin Receptor Agonists are a distinct class of pharmacological compounds designed to selectively bind to and activate one or more of the five subtypes of melanocortin receptors (MC1R to MC5R) found throughout the body, thereby mimicking the therapeutic action of endogenous melanocortin peptides. These agonists are clinically developed to leverage the receptors’ diverse physiological roles in processes such as skin pigmentation, energy homeostasis, sexual function, and the modulation of inflammation. Their development holds significant promise for treating a range of conditions from obesity to specific forms of sexual dysfunction.