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Melanocortin Peptides

Meaning

Melanocortin Peptides are a family of biologically active peptide hormones derived from the precise proteolytic cleavage of a common precursor protein, Pro-opiomelanocortin (POMC). These peptides, which include $alpha$-MSH, $beta$-MSH, $gamma$-MSH, and ACTH, function as crucial neuromodulators and hormones that regulate a diverse range of physiological functions. Their actions encompass control over pigmentation, energy homeostasis, appetite, sexual function, and the systemic stress response, illustrating their widespread influence in endocrinology.