Question 1

What is the Meaning of Meiotic Spindle?

Accepted Answer

The transient highly organized microtubule structure that forms within the oocyte or spermatocyte during meiosis essential for the accurate segregation of homologous chromosomes and sister chromatids into daughter cells. Its integrity is paramount for maintaining euploidy a prerequisite for successful fertilization and embryonic development. Dysfunction in spindle assembly directly correlates with aneuploidy rates.

Question 2

What is the Origin of Meiotic Spindle?

Accepted Answer

This structure is named for its resemblance to a weaver's spindle and meiotic specifies that it forms during the reductional and equational divisions of meiosis rather than mitosis. It is a core component of the cellular machinery governing gamete formation placing it at the center of reproductive cell biology. The term describes its function in chromosome separation.

Question 3

What is the Mechanism of Meiotic Spindle?

Accepted Answer

The spindle apparatus is built from microtubules nucleated around the centrosomes or in many oocytes from acentrosomal microtubule organizing centers. These microtubules capture kinetochores on the chromosomes generating the bipolar tension required for alignment at the metaphase plate. Proper tension sensing ensures that anaphase proceeds only when all chromosomes are correctly attached thereby guaranteeing equitable genetic distribution to the resultant haploid gametes.

Meiotic Spindle

Meaning

Origin

Mechanism

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