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Mechanical Transduction

Meaning

Mechanical Transduction is the fundamental cellular process by which physical forces—such as the tension from exercise, the compression from gravity, or the shear stress of fluid flow—are converted into specific biochemical signals that alter cell function, gene expression, and tissue structure. This process is absolutely essential for maintaining the structural integrity and adaptive capacity of mechanically sensitive tissues, including bone, skeletal muscle, and the vascular endothelium. In the context of endocrinology, it is particularly relevant for understanding how physical activity influences anabolic hormone signaling and tissue remodeling.