Skip to main content

Mechanical Loading

Meaning

Mechanical Loading is the application of external or internal physical forces, including tension, compression, and shear stress, onto musculoskeletal and connective tissues, serving as a powerful physiological stimulus for adaptive remodeling. In the context of hormonal health, this force-induced stimulus is critical for maintaining skeletal integrity, enhancing muscle protein synthesis, and favorably modulating the systemic endocrine environment. Insufficient mechanical loading leads to a catabolic state, contributing to bone mineral density loss and sarcopenia.