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MCHR1

Meaning

MCHR1 stands for the Melanin-Concentrating Hormone Receptor 1, a specific type of G protein-coupled receptor prominently expressed in the central nervous system, particularly in hypothalamic regions crucial for energy homeostasis and complex behavior. This receptor serves as the binding site for the neuropeptide melanin-concentrating hormone (MCH) and plays a fundamental role in regulating appetite, promoting food intake, and modulating overall energy expenditure. Modulating MCHR1 activity is a significant therapeutic target for managing weight and metabolic disorders.