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Maximal Output Strategy

Meaning

Maximal Output Strategy refers to a clinical or pharmacological approach specifically designed to elicit the highest possible physiological response from an endocrine system or target tissue, often by administering agents at or near the maximum tolerated dose. This strategy aims for a rapid, supra-physiological effect, such as maximizing muscle protein synthesis or stimulating maximal endogenous hormone release, typically for a defined, short period. While effective for acute performance goals, this approach carries a significantly higher risk of adverse effects and often compromises long-term homeostatic balance.