Matrixyl 3000 is a proprietary, clinically studied cosmetic ingredient complex composed of two specific signal peptides, Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7. This blend is recognized for its ability to mimic the skin’s natural communication processes, acting as a messenger to dermal cells. Its primary function is to stimulate the synthesis of key extracellular matrix components, which are essential for youthful skin structure.
Origin
This ingredient was developed in the early 2000s by Sederma, originating from advanced peptide research in cosmetic science focused on non-invasive, topical anti-aging solutions. The name reflects its matrix-targeting function and its designation as an advanced generation of the original Matrixyl peptide.
Mechanism
The two constituent peptides work synergistically by binding to specific receptor sites on dermal fibroblasts. Palmitoyl Tripeptide-1 encourages the production of collagen, while Palmitoyl Tetrapeptide-7 modulates the inflammatory response that can lead to matrix degradation. This dual-action signaling effectively jump-starts the skin’s own repair processes, leading to increased production of collagen, elastin, and hyaluronic acid for visible structural improvement.
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