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Mass Spectrometry

Meaning

Mass Spectrometry is a highly sensitive and precise analytical technique used to measure the mass-to-charge ratio of ions, allowing for the accurate identification and quantification of molecules within a complex biological sample. In clinical endocrinology, this technology, often coupled with liquid chromatography (LC-MS/MS), provides the gold standard for measuring low-concentration steroid hormones and their metabolites with unparalleled specificity, minimizing interference from cross-reacting compounds. This diagnostic precision is crucial for managing complex hormonal conditions and tailoring individualized hormone replacement therapies.
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What Are the Key Differences in NMPA Requirements for Chemically Synthesized versus Recombinant Peptides?

What Are the Key Differences in NMPA Requirements for Chemically Synthesized versus Recombinant Peptides?

NMPA requirements differentiate based on peptide origin, with chemically synthesized peptides emphasizing purity and recombinant peptides requiring extensive immunogenicity and host cell impurity characterization.
∞ NMPA Guidelines
∞ Center for Drug Evaluation
∞ Clinical Trials
HRTio
August 25, 2025