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Mass Spectrometry

Meaning

Mass Spectrometry is a highly sensitive and precise analytical technique used to measure the mass-to-charge ratio of ions, allowing for the accurate identification and quantification of molecules within a complex biological sample. In clinical endocrinology, this technology, often coupled with liquid chromatography (LC-MS/MS), provides the gold standard for measuring low-concentration steroid hormones and their metabolites with unparalleled specificity, minimizing interference from cross-reacting compounds. This diagnostic precision is crucial for managing complex hormonal conditions and tailoring individualized hormone replacement therapies.