A precision approach to balancing sex hormone profiles—testosterone, estrogen, DHEA, and progesterone—to maximize vitality, body composition, and sexual function appropriate for the individual’s biological sex and life stage. This requires nuanced clinical titration beyond simple deficiency correction.
Origin
This term integrates endocrinology across both sexes, recognizing that optimal function in males requires appropriate estrogen metabolism and that female vitality is often supported by robust DHEA and balanced testosterone alongside estrogen. It addresses the dimorphism of endocrine needs.
Mechanism
For males, optimization often involves managing aromatization to prevent excessive estradiol conversion while ensuring sufficient androgen action. In females, the mechanism centers on achieving adequate free androgen influence for libido and energy, balanced against sufficient estrogenic support for bone and cardiovascular health. This requires precise monitoring of circulating and free hormone fractions.
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