Male Andropause Management is the clinical strategy employed to address the constellation of symptoms associated with the gradual decline in testicular steroidogenesis and resultant androgen deficiency in aging males. This management often involves monitoring serum testosterone, SHBG, and LH/FSH levels to assess the integrity of the HPG axis. The goal is to restore symptomatic relief and maintain physiological function, such as libido, bone density, and lean body mass, without inducing adverse erythropoiesis or prostate changes. Careful titration is essential to mimic natural pulsatile release.
Origin
The term “andropause” reflects a conceptual parallel to female menopause, denoting an endocrinological transition phase in later life, although the decline is typically more gradual. Management protocols have evolved from crude testosterone supplementation to sophisticated, personalized replacement strategies informed by modern assay technology. Its clinical relevance stems from the widespread impact of declining androgen levels on long-term male health metrics.
Mechanism
Management typically involves administering exogenous testosterone via injections, gels, or pellets to elevate circulating levels into a healthy physiological range. This exogenous support suppresses endogenous LH and FSH secretion via negative feedback at the pituitary level. Successful application requires monitoring hematocrit and prostate-specific antigen (PSA) to mitigate risks associated with supraphysiological dosing or excessive androgen conversion to dihydrotestosterone.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.