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Magnesium and IGF-1

Meaning

Magnesium and IGF-1 refers to the interconnected biological relationship between the essential mineral magnesium and Insulin-like Growth Factor 1, a key anabolic hormone critical for growth, cellular proliferation, and anti-aging pathways. Magnesium serves as a vital co-factor in numerous enzymatic reactions, including those involved in the synthesis and action of growth hormone and its downstream effector, IGF-1. Clinical evidence suggests that suboptimal magnesium status can impair the signaling efficiency of the growth hormone/IGF-1 axis, potentially contributing to age-related muscle loss and metabolic dysfunction. Maintaining adequate magnesium levels is therefore a supportive strategy for optimizing anabolic hormonal signaling and musculoskeletal health.