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MA.27 Trial

Meaning

The MA.27 Trial is a prominent, large-scale, randomized, phase III clinical trial conducted within the field of breast cancer research, specifically focusing on adjuvant endocrine therapy for postmenopausal women. This study compared two different aromatase inhibitors, anastrozole and exemestane, in patients with hormone receptor-positive early breast cancer. The findings provided crucial comparative efficacy and safety data, directly influencing the standard of care for endocrine management in this patient population.