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Luteinizing Hormone Feedback Loop

Meaning

The Luteinizing Hormone Feedback Loop is the intricate endocrine regulatory system centered on Luteinizing Hormone (LH), a gonadotropin released by the anterior pituitary gland. LH stimulates steroidogenesis in the gonads—testes in males and ovaries in females—which in turn produces sex steroids like testosterone and estrogen. The circulating levels of these sex steroids then signal back to the pituitary and hypothalamus, modulating the release of GnRH and LH itself. This precise, oscillating loop is fundamental to reproductive and overall hormonal health.