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HRTioOctober 5, 2025
Low Testosterone Dementia Risk
Meaning
This clinical correlation describes the observed epidemiological association between sub-optimal or pathologically low circulating levels of testosterone in aging men and an increased probability of developing various forms of cognitive decline, including dementia. Testosterone is a critical neurosteroid; its deficiency is linked to adverse changes in brain structure, function, and amyloid pathology. This association underscores the neuroprotective role of androgens in maintaining long-term cognitive health.
Provided by the clinical team
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