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Low-Grade Inflammation Markers

Meaning

Low-Grade Inflammation Markers are measurable biological indicators, such as high-sensitivity C-Reactive Protein (hs-CRP), interleukin-6 (IL-6), or fibrinogen, whose subtle, chronically elevated levels signal a persistent, non-acute systemic immune activation. This low-grade, or smoldering, inflammation is scientifically recognized as a key driver of biological aging and is mechanistically linked to the development of insulin resistance, endothelial dysfunction, and the degradation of crucial hormonal receptor sensitivity. Clinical practice focuses intently on reducing these markers to mitigate chronic disease risk and enhance overall metabolic health.