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Longitudinal Biomarker Reliability

Meaning

Longitudinal Biomarker Reliability refers to the critical clinical requirement that a specific biological marker maintains consistent and accurate predictive power when measured repeatedly over an extended period in the same individual. This reliability is paramount for the practice of personalized medicine, as it ensures that observed changes in the biomarker, such as shifts in a hormone level or an inflammatory cytokine, genuinely reflect a change in the patient’s underlying physiological state rather than simple measurement variability. Reliable longitudinal data is the cornerstone for accurately assessing the efficacy of any long-term hormonal or wellness intervention and confidently charting a patient’s long-term health trajectory.