Longevity Systems encompasses the integrated network of physiological processes, including hormonal axes and cellular maintenance pathways, that collectively dictate the rate of aging and potential lifespan. These systems must operate in precise coordination.
Origin
This framework is derived from systems biology approaches applied to the study of aging, moving beyond single-gene theories to view longevity as an emergent property of complex interactions.
Mechanism
Effective Longevity Systems rely on tight feedback control within the endocrine feedback loops, efficient DNA repair mechanisms, and minimal accumulation of senescent cells that disrupt local tissue signaling.
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