What is the Origin of Longevity Signaling Molecules?

This terminology is central to modern longevity research, identifying specific targets—like $text{mTOR}$, $text{AMPK}$, or sirtuins—that regulate aging phenotypes. The focus is on influencing the core biology of senescence.

What is the Mechanism of Longevity Signaling Molecules?

These molecules operate by altering transcription factor activity or enzyme function to promote cellular maintenance. For example, some signals enhance mitochondrial quality control through mitophagy or stimulate DNA repair pathways. By favorably shifting the balance toward anabolism and repair, they effectively slow the rate of molecular damage accumulation.

Longevity Signaling Molecules ∞ Area

Longevity Signaling Molecules

Meaning

Molecular entities, both endogenous and exogenous, that directly modulate cellular pathways associated with extending healthspan and promoting intrinsic repair mechanisms. These signals govern how cells respond to metabolic challenges and environmental stressors. They are the molecular switches for biological endurance.