Skip to main content

Longevity Signaling Integrity

Meaning

Longevity Signaling Integrity describes the optimal, precise function of the interconnected cellular pathways—such as mTOR, AMPK, sirtuins, and FOXO transcription factors—that regulate cellular stress response, repair mechanisms, and metabolic adaptation to promote healthspan and resilience. This integrity is maintained when these pathways communicate clearly and respond appropriately to metabolic and environmental cues, free from the disruptive noise of chronic inflammation or chronic toxin load. Maximizing this integrity is the ultimate goal of physiological baseline tuning.