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Longevity Set Point

Meaning

The Longevity Set Point is a conceptual and clinically derived physiological baseline representing an individual’s intrinsic, genetically and epigenetically determined level of cellular repair, metabolic efficiency, and systemic resilience against age-related decline. This set point is a measure of the organism’s homeostatic tendency to maintain a state of health and function, reflecting the collective output of core longevity pathways. Clinical interventions aim to deliberately raise this set point, thereby increasing the duration of the functional health span.