What is the Origin of Longevity Science Endocrinology?

This is a newly defined intersection of traditional endocrinology, which studies hormones, and longevity science, which studies the mechanisms of aging. It emerged from the realization that hormonal decline is a primary driver, not just a consequence, of aging. The focus is on regulatory hormones like Growth Hormone, IGF-1, DHEA, and the sirtuins.

What is the Mechanism of Longevity Science Endocrinology?

Longevity endocrinology seeks to optimize the balance of anabolic and catabolic hormones, often targeting pathways like the Growth Hormone/IGF-1 axis and the insulin/mTOR pathway, which are known to influence cellular senescence and tissue repair. Interventions are designed to restore youthful signaling patterns, enhance cellular resilience, and maintain metabolic flexibility, thereby extending the duration of healthy, functional life.

Longevity Science Endocrinology ∞ Area

Longevity Science Endocrinology

Meaning

A specialized field of endocrinology focused on the role of hormones and their signaling pathways in the process of biological aging and the maintenance of healthspan. This discipline investigates how age-related changes in hormone production, receptor sensitivity, and metabolic feedback loops contribute to the decline in physiological reserve and the onset of chronic disease. The goal is to identify and modulate key endocrine targets to slow the aging process.