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Longevity Paradox

Meaning

The Longevity Paradox is an epidemiological observation that individuals exhibiting certain clinical or physiological characteristics, which are conventionally associated with poor health outcomes or increased mortality risk, unexpectedly demonstrate a prolonged lifespan. This counterintuitive finding highlights the profound complexity of the aging process and the need to differentiate between biological markers of disease and compensatory adaptations that may confer survival benefits. In the context of hormonal health, it often relates to the observation that lower levels of certain anabolic hormones in later life may not always correlate with a reduced lifespan.