What is the Origin of Longevity Hormones?

This designation stems from clinical and epidemiological research that observed a correlation between robust levels of certain hormones and better health outcomes in centenarians and long-lived populations. It provides a functional grouping for hormones that are not merely regulatory but are fundamentally protective against the hallmarks of aging. The concept underpins targeted hormonal optimization in anti-aging protocols.

What is the Mechanism of Longevity Hormones?

These hormones operate by modulating critical longevity pathways within the cell. For instance, DHEA acts as a precursor to sex steroids and possesses anti-glucocorticoid effects, helping to mitigate chronic stress damage. Growth hormone and its effector, IGF-1, drive tissue repair and regeneration. Maintaining optimal signaling of these longevity hormones supports metabolic flexibility, enhances immune surveillance, and promotes the cellular maintenance necessary to delay senescence.

Longevity Hormones

Meaning

Longevity Hormones is a collective term used to describe a specific group of endocrine signaling molecules whose optimal levels and functional signaling capacity are strongly correlated with extended healthspan and protection against age-related diseases. These hormones, which often decline with age, play pivotal roles in metabolism, cellular repair, and systemic resilience. Key examples include DHEA, growth hormone, melatonin, and optimal thyroid hormones.