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Longevity Gene Pathways

Meaning

Longevity Gene Pathways refer to the interconnected, evolutionarily conserved molecular signaling cascades regulated by specific genes that collectively modulate the rate of biological aging and confer resistance to age-related diseases. These pathways are central to the clinical science of life extension, governing fundamental cellular processes like DNA repair, nutrient sensing, stress response, and metabolic efficiency. Key examples include the sirtuins, mTOR, and AMPK signaling networks, which are highly responsive to environmental and nutritional modulation. Optimizing these pathways is the cornerstone of a precision health approach to maximizing healthspan.