What is the Origin of Longevity Enhancement?

Drawing from biogerontology, the concept has evolved from simple lifespan extension to a focus on maintaining physiological vigor late into life. The 'enhancement' implies active intervention rather than passive aging.

What is the Mechanism of Longevity Enhancement?

Interventions often modulate nutrient sensing pathways like the AMPK and mTOR pathways, influencing cellular repair mechanisms like autophagy. Furthermore, optimizing key anabolic hormones and reducing chronic low-grade inflammation, a hallmark of aging, contributes to maintaining tissue function. This systemic optimization supports cellular resilience against accumulated damage.

Longevity Enhancement

Meaning

Longevity Enhancement is the application of evidence-based interventions aimed at slowing the rate of biological aging and extending the period of optimal healthspan, not merely chronological lifespan. This involves targeting fundamental aging pathways such as cellular senescence, telomere attrition, and metabolic flexibility. We aim to compress morbidity into the final stages of life.