Longevity Chemistry Protocols are clinically guided, evidence-based regimens that utilize specific pharmaceutical, nutraceutical, and lifestyle interventions to optimize key biomarkers associated with the biological processes of aging. These protocols move beyond general wellness to target fundamental aging pathways, such as cellular senescence, mitochondrial dysfunction, and telomere attrition. The ultimate goal is to compress morbidity and extend healthspan by maintaining youthful hormone kinetics.
Origin
This term represents the practical application of translational research from the fields of gerontology, molecular biology, and endocrinology. It signifies a shift in clinical focus from treating age-related disease to proactively managing the underlying chemistry of the aging process itself.
Mechanism
The protocols function by modulating specific signaling molecules, including AMPK, mTOR, and sirtuins, which govern cellular metabolism and stress resistance. They often involve precise hormonal replacement therapies to maintain levels within the physiological hormone range, counteracting the age-related decline that drives systemic deterioration. This chemical management aims to preserve tissue function and reduce chronic inflammation, a primary driver of age-related pathology.
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