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Longevity Biochemistry Pathways

Meaning

Longevity Biochemistry Pathways represent the interconnected, evolutionarily conserved cellular signaling cascades that govern the rate of aging and the resilience of an organism against chronic disease. These pathways include key regulators such as mTOR, AMPK, sirtuins, and the insulin/IGF-1 axis, which collectively integrate nutrient availability, energy status, and stress signals to modulate cellular repair, metabolism, and survival. Clinical strategies targeting these pathways aim to promote healthspan by enhancing cellular housekeeping and stress resistance mechanisms. Understanding these cascades is foundational to the science of healthy aging.