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Long-Term Safety Efficacy

Meaning

Long-Term Safety Efficacy is a critical clinical metric that evaluates the sustained benefit and minimal adverse risk profile of a therapeutic intervention, particularly hormonal or metabolic treatments, over an extended period of years or decades. This assessment moves beyond short-term symptomatic relief to ensure that the intervention maintains its positive effect while not introducing unforeseen or accumulating risks to cardiovascular, oncological, or bone health. It is the cornerstone of responsible, evidence-based practice in longevity and preventative medicine.